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š§ The Similarities Between Migraine and Seizures...
The tale of how different conditions share similar neurology and patterns of inflammation

Your hub for natural migraine management. More Relief. Less Medication.

Hey Migraine Mentees š
Todayās newsletter takes 4 minutes and 32 seconds to read, but if youāve only got 60 seconds, hereās what you need to know:
Migraine attacks and seizures share similar neurological and inflammatory pathwaysā¦
With that said, theyāre still separate conditions but share similar geneticsā¦
Treatments often overlap due to these similaritiesā¦
While genetics load the āgun,ā the environment often pulls the ātriggerā for symptomsā¦
Weāve been posting about this one for a while now and weāve been generating A LOT of discussions around this topicā¦
š§ The Migraine Mentors
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In This Weekās Editionā¦
š„” Weekly Take-Out
Meme of The Week - You Shall Not Passā¦
š£ļø This Weekās Sponsor
The Neural Connection Clinic - š„¼ Youāre Potentially One Step Away From Reliefā¦
šø Weekly TikToks
Is Migraine a Different Form of Seizures?
Objective VNG (Visual) Testing for Migraine and Headaches
šļø The Migraine Mentors Minicast - Podcast Series
Why Seizures and Migraine Symptoms Are Similar, Yet Differentā¦
š This Weekās Top Article
The Similarities Between Migraine and Seizuresā¦
š“ Migraine-Friendly Recipe of the Week
Fresh Frozen Fruit Bars

š„” WEEKLY TAKE-OUT
Meme of The Week


š«° CLINIC SPONSOR
The Neural Connection Clinic
The Neural Connection is a world-class Functional Neurology clinic in Edina, MN.
What is Functional Neurology, you ask?!
A functional neurologist is who you see when your medical neurologist says youāre āfineā but you still have symptoms.
š§ The Neural Connection clinic specializes in holistic migraine, headache, and concussion management by addressing the root causes, not just the symptoms.
By examining you structurally, neurologically, and metabolically, they can provide you with a personalized treatment plan to help you finally regain your health.
But donāt take their word for itā¦
Hereās one of the 100+ 5-Star āļøāļøāļøāļøāļø Google Reviews from a woman who was having 25 migraines a month (Sound familiarā¦?):
āI came for migraines and learned so much that Western medicine doesnāt teach you. Iām a primary care doc that left with so much more knowledge.ā
šļø If youāre ready to take the next step and finally find the answers youāve been looking for, click below to set up a free consultation with one of their doctors!

š„” WEEKLY TIKTOKS
Is Migraine a Different Form of Seizures?
@themigrainementor #greenscreen #migraine #migrainerelief #vestibularmigraine #migraines #brain #seizure #seizures #pain #chronicillness
Objective VNG (Visual) Testing for Migraine and Headaches
@headache_whisperer VNG testing is my favorite way to guide rehab. It tells us whatās not working and how dysfunctional it is. This is hugely important in r... See more

šļø MIGRAINE MINICAST
Why Seizures and Migraine Symptoms Are Similar, Yet Differentā¦
Migraine and epilepsy may seem like entirely different conditions, but they share striking similarities in how they affect the brainā¦
š§ In this weekās episode, we explore the neurological connection between migraine and epilepsy, examining their overlapping triggers, shared brain pathways, and why certain treatments are effective for both.
Weāll also discuss key insights into how these conditions are managed and what this means for those looking for better treatment optionsā¦
šļø Click the link below to check it out! šļø

š TOP ARTICLE
The Similarities Between Migraine and Seizuresā¦
At first glance, migraine and epilepsy seem like completely different conditionsāone brings pounding headaches, the other involves seizures.
But what if we told you they share a lot more than you think�
Both conditions are linked by similar brain activity, genetic factors, and even dietary triggers.
In fact, doctors often describe them as neurological cousins because they affect the brain in many of the same ways.
Weāre going to break down why migraine and epilepsy are more connected than most people realizeā¦
𧬠The Genetics - If You Have One, You Might Be Prone to the Other
Ever wonder why migraines or epilepsy seem to run in families?
Thatās because both are influenced by genes that affect how brain cells fire and communicate.
Some of the key genes they share control:
ā”ļø How brain cells send signals (Too much or too little activity can lead to migraine attacks or seizures.)
ā”ļø How blood vessels work in the brain (Changes in blood flow can trigger both conditions.)
ā”ļø How the brain processes pain and stress (Making some people more sensitive to attacks.)
If a close family member has migraine symptoms, your brain may already be wired to be extra sensitive to triggersāwhich is also true for epilepsy.
š Brain Waves & Storms - Whatās Really Happening During an Attack
One of the biggest connections between migraine and epilepsy is something called cortical spreading depression (CSD)āa fancy term for a ābrain wave disturbance.ā
Hereās what happens:
š A sudden wave of overactive brain activity spreads like ripples on a pond.
š Itās followed by a shutdown of brain activity.
ā” This can lead to migraine aura (flashing lights, tingling, speech trouble) or, in epilepsy, a seizure.
Both conditions involve brain overexcitement, which explains why people with migraines often feel totally wiped out after an attackājust like someone who has had a seizure.
𩸠Blood Flow & Brain Chemistry - The Common Thread
Migraine and epilepsy donāt just share genetics and brain wave disturbancesāthey also mess with blood flow and brain chemicals in similar ways.
š¹ Blood Flow Changes ā In both conditions, the brainās blood vessels tighten and relax unpredictably, which can lead to pain, dizziness, or even vision problems.
š¹ Too Much Glutamate (The Brainās Gas Pedal) ā This chemical excites brain cells. Too much of it? Itās like flooring the gas pedal on a car with no brakesāleading to either a migraine attack or a seizure.
š¹ Not Enough GABA (The Brainās Brake Pedal) ā This calming chemical helps slow down brain activity. When thereās not enough, the brain becomes overactive, making seizures and migraines more likely.
ā ļø Common Triggers - Why the Same Things Set Off Both Conditions
Because migraine and epilepsy affect the brain in similar ways, itās no surprise that many of the same things can trigger attacks.
šØ Top Triggers They Share:
Lack of sleep (Sleep helps the brain reset. Without it, attacks are more likely.)
Hormone shifts (Estrogen changesālike during a menstrual cycleācan set off both migraines and seizures.)
Alcohol & caffeine (They alter brain chemicals and blood flow.)
Bright or flashing lights (Ever wonder why some people get headaches from strobe lights? This is why.)
Dehydration & fasting (Not eating or drinking enough can mess with the brainās balance.)
Thereās even a rare condition called migralepsy, where a migraine directly triggers a seizure⦠Although this is very uncommon!
š Why Some Epilepsy Medications Work for Migraines
Because the brain dysfunction in migraine and epilepsy is so similar, some of the same medications work for both.
For example:
ā
Topiramate (Topamax) ā Originally made for epilepsy, but doctors found it also helps prevent migraines.
ā
Valproate (Depakote) ā Used to stabilize brain activity in both conditions.
ā
CBD & Cannabinoids ā Studies show that CBD can calm brain inflammation and reduce both migraines and seizures.
ā¤ļøā𩹠The Takeaway - What This Means for You
If you suffer from migraines, understanding their deep connection to epilepsy can help you:
š” Recognize shared triggers and avoid things that might set off an attack.
š” Look at treatment options differentlyāsome epilepsy treatments may work for migraines.
š” Understand your brain better and why these attacks happen in the first place.
Itās important to understand that while migraine and seizures share these similarities, theyāre still different conditions and must be treated that way.
Fortunately for you, most of the treatments that work for one can also work for the other!

š“MIGRAINE-FRIENDLY RECIPE
Fresh Frozen Fruit Bars

š„£ Ingredients
2 cups fresh fruit (e.g., strawberries, bananas, or peaches)
1 cup coconut water or unsweetened almond milk
1-2 tablespoons honey or maple syrup (if tolerated)
š Instructions
Blend the fresh fruit and coconut water/almond milk until smooth.
Pour the mixture into popsicle molds and freeze for several hours until solid.
To serve, run warm water over the outside of the molds to loosen and remove the bars.
šļø Notes
Sweeteners
Keep in mind that sweeteners like honey and maple syrup should be used in moderation and may or may not be tolerated by everyone.
Fruits
Fresh fruits are generally safer choices compared to dried fruits due to lower histamine levels.
Experimentation
Always consider personal tolerance levels. Individual responses to certain ingredients can vary based on individual sensitivities, so it may be necessary to adjust ingredients according to what works best for you.
šŖ The Health Benefits
Why Itās Migraine and Histamine Friendly
Fresh and Natural Ingredients
This recipe avoids common migraine triggers like chocolate, caffeine, aged dairy, and processed sugars, focusing instead on simple, fresh components.
No Artificial Ingredients
Unlike many store-bought frozen desserts that may contain additives, artificial flavorings, and preservativesāknown migraine triggersāthese bars rely solely on fresh fruit and natural sweeteners.
Low-Histamine Base
The combination of fresh ingredients minimizes the risk of histamine build-up. Homemade foods avoid the histamines often found in pre-packaged or processed snacks.
Control of Ingredients
You can ensure that every component of the recipe is fresh, thus reducing the risk of histamine reactions that might come from older or fermented ingredients.

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