Hey Migraine Mentees 👋 

Today’s newsletter takes about 5 minutes to read—so if you’ve only got 60 seconds, here’s what you need to know:

• Histamine is a powerful immune chemical that can trigger migraines by dilating blood vessels, inflaming nerves, and increasing brain sensitivity…

• It’s naturally produced by the body—but certain foods, gut imbalances, hormone shifts, and nutrient deficiencies can cause histamine to build up too quickly…

• Common signs of histamine sensitivity include headaches after wine or leftovers, skin flushing, digestive issues, anxiety, and dizziness after meals…

• Over-the-counter antihistamines may help temporarily—but root-cause strategies like a low-histamine diet, DAO support, and gut repair are more effective long-term…

• Identifying and managing histamine overload can significantly reduce migraine frequency, pain intensity, and random flare-ups…

This week, we’ll show you how to recognize histamine intolerance—and what to do when your nervous system is inflamed from the inside out.

🧠 The Migraine Mentors

First time reading?! Sign up HERE.

In This Week’s Edition…

• 🥡 Weekly Take-Out

  • Meme of The Week - 🤮 Nausea, amiright?!

• 📸 Weekly TikToks

  • Why You Haven’t Tried “Everything” For Managing Migraines…

  • From 26 Migraines a Month to 0 in Less Than 3 Weeks…

• 🔈️ The Migraine Mentors Minicast - Podcast Series

  • Histamine – The Migraine Trigger Hiding in Plain Sight?

• 📜 This Week’s Top Article

  • The Role Histamine Plays in Migraine & Chronic Pain

• 🍴 Migraine-Friendly Recipe of the Week

  • Pear & Oat Smoothie

🥡 WEEKLY TAKE-OUT

Meme of The Week

🥡 WEEKLY TIKTOKS

Why You Haven’t Tried “Everything” For Managing Migraines…

@drerikreis

You HAVEN’T tried it all…! I promise you that… Why? Most healthcare providers are like hammers looking for a nail - they've got ONE tool,... See more

From 26 Migraines a Month to 0 in Less Than 3 Weeks…

@headache_whisperer

#migraine #migrainerelief #migrainerelieftok #headacherelief #greenscreen #ConSantanderConecto

🗞️ MIGRAINE MINICAST

🎧 Histamine – The Migraine Trigger Hiding in Plain Sight?

🥡 When dealing with chronic migraines, what if the issue isn’t the food itself, but how your body handles it?

🧠 This week, we’re spotlighting histamine—a powerful immune compound that can fuel inflammation, nerve sensitivity, and chronic migraine pain when it builds up unchecked.

Here’s what we cover in today’s episode:

• How histamine interacts with the nervous system—and why it's not just an “allergy” issue…

• The connection between gut health, hormones, and histamine overload…

• Why too much histamine can trigger migraines, nausea, dizziness, and anxiety…

• Common signs of histamine sensitivity most people miss…

• 3 root-cause strategies to reduce histamine without overusing antihistamines…

🧩 If your migraines feel random or flare up after certain foods, stress, or weather—histamine could be your missing puzzle piece.

🎯 Tune in and learn how to bring your system back into balance—naturally.

👇 Tap below to listen now! 👇

📜 TOP ARTICLE

The Role Histamine Plays in Migraine & Chronic Pain

Why this little known immune compound might be inflaming your nervous system—and how to calm it down…

You didn’t skip sleep. You didn’t forget to hydrate.

But after that glass of wine or day-old leftovers, the migraine came anyway…

What if the problem isn’t what you ate—but how your body responded?

It’s time to talk again about histamine—a little-known but powerful player in the migraine and chronic pain cycle.

🧠 What is Histamine?

Histamine is a natural compound made by immune cells, especially mast cells.

It plays a key role in:

• Widening blood vessels (vasodilation)

• Triggering inflammation

• Sending pain signals

• Influencing digestion and mood

Normally, your body breaks it down using an enzyme called DAO (diamine oxidase)…

But in many people with chronic migraine, histamine builds up faster than it can be cleared.

The result?

A hyper-sensitive nervous system that’s constantly under fire…

🔁 Histamine and Migraine - A Vicious Cycle

While too little histamine can be an issue, too much histamine can:

• Dilate brain vessels → trigger migraines

• Activate sensory nerves → worsen light/sound sensitivity

• Affect gut-brain signaling → lead to nausea and bloating

• Ramp up inflammation → keep pain going long after the trigger's gone

Add in things like stress, hormonal changes, or gut issues—and your histamine “bucket” spills over, flooding your system…

Causing, you guessed it… Migraines.

⚠️ Signs Histamine Might Be a Problem

We often hear migraine patients reporting the following issues when dealing with histamine intolerances:

• Headaches after aged or fermented foods

• Itchy skin or flushing

• Sinus congestion without illness

• GI issues like bloating or diarrhea

• Anxiety, panic, or insomnia

• Dizziness after meals or with heat

If this sounds familiar, histamine may be part of your pain story too…

So what can you do about it?

🌩️ How to Calm the Fire Before The Storm

You don’t have to rely on antihistamines forever… And to be honest, we suggest you don’t.

Here’s how to get at the root causes of histamine intolerances causing chronic migraine symptoms:

1. Support DAO Function

Nutrients like vitamin B6, magnesium, and vitamin C help your body break down histamine. Avoiding alcohol is also key—it blocks DAO!

2. Try a Low-Histamine Diet

Limit or rotate foods like aged cheese, leftovers, kombucha, wine, and canned fish for 2–4 weeks to see if symptoms improve. If they do, there’s a high chance you have a histamine intolerance and should consider other food choices…

3. Heal the Gut

While easier said than done, this one is worth it. Leaky gut, mold, and SIBO are often hidden drivers.

*Self Promoting Plug: At The Neural Connection, we run functional blood chemistry testing to get clarity and design targeted protocols to restore balance.

✅ Information is Great, but You Need to Take Action…

If you’ve tried “all the things” and are still dealing with chronic digestive issues, gut dysfunction, and food sensitivities… Histamine may be the missing link in your migraine puzzle.

Start with a short elimination trial…

Clean up your gut…

Support your nutrients…

And if you need help figuring it out, you know who to call… (👻 Ghost Busters!)

🧠 The Migraine Mentors

🍴MIGRAINE-FRIENDLY RECIPE

 🍐 Pear & Oat Smoothie

🗒️ Ingredients

• 1 ripe pear (peeled)

• 1/4 cup rolled oats

• 1 tbsp ground flaxseed

• 1 cup oat milk (unsweetened, no gums or additives if possible)

• Dash of cinnamon (optional – skip if you’re sensitive)

Why This Smoothie Is a Gentle Choice

🍐  Pear (peeled)

Pear is one of the lowest histamine fruits and is rarely a migraine trigger. Peeling helps reduce fiber irritants for sensitive guts. It’s a naturally sweet, hydrating base that’s easy to digest.

🥣 Rolled Oats

Oats are a great source of soluble fiber, helping to keep blood sugar stable—important for preventing migraine attacks triggered by drops in blood sugar. They’re also low in histamine and usually well-tolerated.

🌱 Ground flaxseed

Flaxseeds are rich in omega-3s and fiber, both of which support a calm, anti-inflammatory environment in the body. They’re also naturally low in histamine and can help with gut motility, which is often sluggish in migraine sufferers.

🥛  Oat milk

Oat milk (when free from gums and additives) is a safe, dairy-free base. It avoids migraine triggers like casein or whey found in regular dairy. Make sure to choose a clean label brand to minimize additives that may cause reactions.

⚠️ Cinnamon (optional)

Cinnamon can have anti-inflammatory properties, but in rare cases may be a histamine liberator. Try leaving it out at first, then test it in small amounts if you know you’re not sensitive.